Lab Members

Lindquist Lab Members

Postdoctoral Associates and Fellows
	Pavan Auluck, MD, PhD	Rm# 649	auluck at wi.mit.edu	Pavan is interested in yeast models of toxicity associated with diseases of protein folding and is coordinating high-throughput screens for compounds that rescue that toxicity.
	Gabriela Caraveo, PhD	Rm# 649	caraveop at wi.mit.edu	Gabriela is working on the role of calcium signaling in yeast and mouse neuronal models of synucleinopathies.
	Sohini Chakrabortee, PhD	Rm# 659	sohini at wi.mit.edu	Sohini is studying the role of intrinsically disordered proteins during stress.
	Kendra K. Frederick, PhD	Rm# 657	kendrakf at wi.mit.edu	Kendra is using NMR to investigate the mechanisms of oligomer and amyloid fiber formation.
	Aftabul Haque, PhD	Rm# 637	aftab at wi.mit.edu	Aftab is studying the role of intracellular Abeta in cellular toxicity.
	Sven Heinrich, PhD	Rm# 659	heinrich at wi.mit.edu	Sven is investigating the mechanism of prion formation of neuronal CPEB and identifying new regulators of that process.
	Georgios Karras, PhD	Rm# 655	gkarras at wi.mit.edu	Georgios is investigating the molecular mechanisms by which Hsp90 influences genetic variation.
	Can Kayatekin, PhD	Rm# 651	ckayatek at wi.mit.edu	Can is investigating the formation and structure of new classes of prions.
	Vikram Khurana, MD, PhD	Rm# 651	khurana at wi.mit.edu	Vik is interested in stem cell-based therapeutics for neurodegenerative diseases and is collaborating with the laboratory of Rudolf Jaenisch.
	Martina Koeva, PhD		martina at wi.mit.edu	Martina is interested in the computational analysis of gene expression in cancer. She is co-mentored by Dr. Ernest Fraenkel in the Dept. of Biological Engineering at MIT.
	Catherine McLellan, PhD	Rm# 649	mclellan at wi.mit.edu	Catherine is using novel small molecules to probe chaperone function in yeast.
	Marc Mendillo, PhD	Rm# 653	mendillo at wi.mit.edu	Marc is a studying the role of the heat shock response in cancer.
	Lauren Pepper, PhD	Rm# 653	pepper at wi.mit.edu	Lauren is working on N-rich proteins in malaria and coordinating high-throughput screens of inhibitors of malarial heat-shock proteins.
	Sandro Santagata, MD, PhD	Rm# 657	santagat at wi.mit.edu	Sandro is characterizing small-molecule modifiers of the heat-shock response.
	Ruth Scherz-Shouval, PhD	Rm# 655	ruthsh at wi.mit.edu	Ruthie is studying the role of HSF1 in the tumor microenvironment.
	Reut Shalgi, PhD	68-259 MIT	reuts at wi.mit.edu	Reut is working on splicing and translation regulation, and the interplay between them in the mammalian stress response. She is co-mentored by Dr. Chris Burge in the Dept. of Biology at MIT.
	Mikko Taipale, PhD	Rm# 655	taipale at wi.mit.edu	Mikko is investigating how Hsp90 modulates the relationship between genotype and phenotype in human cancer cells.
	Daniel Tardiff, PhD	Rm# 653	tardiff at wi.mit.edu	Dan Tardiff is using yeast and neuronal models to study modulators of TDP-43 proteinopathy.
	Peter Tsvetkov, PhD	Rm# 655	petert at wi.mit.edu	Peter is working on genes regulated by the memory-associated prion, CPEB.

Senior Research Scientists

	Chee-Yeun Chung, PhD	Rm# 649	cychung at wi.mit.edu	Chee-Yeun is studying mechanisms of cell death associated with protein misfolding in mammalian neurons.
	Luke Whitesell, MD	Rm# 663	whitesell at wi.mit.edu	Luke is interested in preventing cancer from being triggered or progressing by targeting cellular stress responses and the molecular chaperones regulated by them.

Staff Scientist

Alex Lancaster, PhD

Rm# 635

alexl at wi.mit.edu

Alex is a computational biologist working on prion evolution.

Graduate Students

Bill Hesse	Rm# 659	wrhesse at mit.edu	Bill is working on optical trapping of amyloid fibers. He is co-mentored by Roger Kamm in the Department of Biological Engineering at MIT and Matthew Lang in the Department of Chemical and Biomolecular Engineering at Vanderbilt.
Greg Newby	Rm# 655	gnewby at wi.mit.edu	Greg is interested in using heritable prions as switches to engineer new expression systems in yeast.
Benjamin Vincent	Rm# 651	bvincent at wi.mit.edu	Ben is probing the heat shock response and the evolution of drug resistance through the characterization of novel small molecules.
Annie Yu	Rm# 653	xyu at wi.mit.edu	Annie is studying amyloid fiber assembly.

Undergraduate Students

Emmanuel Carrodeguas

MIT UROP

Class of 2014

Rm# 657

edeguas at mit.edu

Emmanuel is working on mechanisms of [GAR] prion formation.

Technical Associates

Valeriya Baru	Rm# 637	baru at wi.mit.edu	Lera works on biochemistry and molecular biology of human diseases, differentiation of mouse ES cells, and primary neuronal cell culture.
Yelena Freyzon	Rm# 637	freyzon at wi.mit.edu	Yelena works on in vivo and in vitro models of human diseases and manages the lab mouse colony.
Irina Krykbaeva	Rm# 655	irinak at wi.mit.edu	Irina is working on human disease alleles.
Yali Lou, PhD	Rm# 651	yalilou at wi.mit.edu	Yali is working on stem cell and neuronal differentiation.
Artur Topolszki	Rm# 655	artur at mit.edu	Artur is a vital member of ongoing projects to determine the role of HSF1 in cancer and assists with models of neurodegenerative disease.
Melissa Topolszki	Rm# 655	duquette at mit.edu	Melissa orders consumables and makes reagent stocks essential for the daily running of the lab. She is helping out with a variety of scientific projects including but not limited to studies of HSF1 in cancer, and the nature of cellular toxicity in neurodegenerative disease.

Lab Manager

Brooke Bevis, PhD

Rm# 659

bevis at wi.mit.edu

Brooke is in charge of hiring and orienting new personnel and maintaining the lab's infrastructure. She keeps the lab running smoothly by organizing, problem-solving, and troubleshooting.

Administrative Assistant

Audrey Mc Ardle

Rm# 661

amcardle at wi.mit.edu

Audrey assists Dr. Lindquist and members of the lab with travel arrangements, calendar, reception, and other office and administrative work.

Lab Administrator

Robert Burger

Rm# 661

burger at wi.mit.edu

Bob performs financial accounting, ordering, and personnel management for the Lindquist lab, and liaisons with the Office of Sponsored Programs.

Project Manager, Communications and Grant Development

Linda Clayton, PhD

Rm# 663

lclayton at wi.mit.edu

Linda manages communication and development of scientific activities for the Lindquist Lab. She assists Dr. Lindquist in the preparation of scientific aspects of grants and fellowships and recommendation letters, oversees scientific collaborations, and edits manuscripts.